This research study is looking at whether abelacimab, when compared with a placebo, can help prevent ischemic stroke or systemic embolism in people with AF who are considered unsuitable for standard oral blood thinners.
This is a Phase 3, randomized, double-blind, placebo-controlled study — meaning participants are randomly assigned to receive either abelacimab or a placebo, and neither you nor the study team will know which one you’re getting during the study.
Everyone in the study continues to receive their regular medical care.
The study plans to enroll about 1,900 participants and is expected to continue through late 2026.
Why join? By joining this study, you may help researchers learn whether an investigational treatment can reduce the risk of stroke and other clot-related complications in people with atrial fibrillation who cannot take standard blood thinners. Participants receive study-related medical care at no cost from our experienced clinical team and may be compensated for time and travel.